Role of macrophage migration inhibitory factor in age-related lung disease

Role of macrophage migration inhibitory factor in age-related lung disease.

The prevalence of many common respiratory disorders, including pneumonia, chronic obstructive lung disease, pulmonary fibrosis, and lung cancer, increases with age. Little is known of the host factors that may predispose individuals to such diseases. Macrophage migration inhibitory factor (MIF) is a potent upstream regulator of the immune system. MIF is encoded by variant alleles that occur com...

Macrophage migration inhibitory factor in cardiovascular disease.

The highly conserved and archetypical yet atypical cytokine macrophage migration inhibitory factor (MIF) fulfills pleiotropic immune functions in many acute and chronic inflammatory diseases. Recent evidence has emerged from both expression and functional studies to implicate MIF in various aspects of cardiovascular disease. The present review is aimed at providing a synopsis of the involvement...

CALL FOR PAPERS Biomarkers in Lung Diseases: from Pathogenesis to Prediction to New Therapies Role of macrophage migration inhibitory factor in age-related lung disease

Sauler M, Bucala R, Lee PJ. Role of macrophage migration inhibitory factor in age-related lung disease. Am J Physiol Lung Cell Mol Physiol 309: L1–L10, 2015. First published May 8, 2015; doi:10.1152/ajplung.00339.2014.—The prevalence of many common respiratory disorders, including pneumonia, chronic obstructive lung disease, pulmonary fibrosis, and lung cancer, increases with age. Little is kno...

Macrophage Migration Inhibitory Factor

Macrophage migration inhibitory factor (MIF), a role in COPD

Authors: 5 Gunnar R. Husebø, Per S. Bakke, Rune Grønseth, Jon A. Hardie, Thor Ueland, Pål 6 Aukrust, Tomas M.L. Eagan. 7 8 Dept. of Thoracic Medicine, Haukeland University Hospital, Bergen Norway 9 2 Dept. of Clinical Science, University of Bergen, Norway 10 Research Institute of Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway 11 K.G. Jebsen Inflammatory Research Centre...